Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction, progression, and prion-like spread of Alzheimer s disease pathogenesis
Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson, Gunnar K. Gouras, Melinda Rezeli, Laurent Roybon
The paper uses proteomic analysis of patient iPSC-derived brain cells and post-mortem hippocampal tissue to study early AD pathogenesis and prion-like spread.
Acta Neuropathologica Communications · Sep 15, 2023Peer-reviewedNeuroscience