Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates
Charlotte M. Fischer, Hannes Ausserwöger, Tomas Sneideris, Daoyuan Qian, Rob Scrutton, Seema Qamar, Peter St George-Hyslop, Tuomas P. J. Knowles
The paper investigates how temperature affects G3BP1-RNA phase separation, revealing that while the phase boundary remains stable, stoichiometry and energetics shift, driven by entropic processes.
bioRxiv · Feb 2, 2024 · PreprintBiophysics