BiochemistryOpen BiologyPeer-reviewed
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body
Alexander Stadler, Laryssa Vanessa de Liz, Heloisa B. Gabriel…·Gang Dong
This study determines the structure of CFAP410's C-terminal domain and shows that its tetrameric helical bundle is essential for basal body localization, explaining how the L224P mutation causes ciliopathies.