Bojan Žagrović

The paper demonstrates that protein kinases can undergo intramolecular autophosphorylation using single-molecule reaction chambers, challenging the conventional view of intermolecular activation.

This study uses molecular dynamics simulations to show that the FUS RGG3 IDR forms a dynamically organized dense phase with defined interaction motifs and multi-scale topology.

This study reveals that PHLPP2 is a pseudophosphatase with no catalytic activity, challenges its role as a tumor suppressor, and identifies its non-catalytic functions in Akt signaling.

This study determines the structure of CFAP410's C-terminal domain and shows that its tetrameric helical bundle is essential for basal body localization, explaining how the L224P mutation causes ciliopathies.

This study identifies FIBCD1 as a conserved receptor for chondroitin sulphate proteoglycans in the brain ECM, linking it to neurodevelopmental disorders through genetic and functional analyses.

The paper shows that key physicochemical properties of protein sequences remain robust against +1 and -1 frameshifts, suggesting frameshifting could be an evolutionary mechanism for generating new proteins with similar properties.