Gang Dong

The paper investigates genetic conflict between toxin-antidote elements in C. tropicalis, revealing their role in shaping hyperdivergent haplotypes through competition and recombination.

The paper shows how a duplicated tRNA synthetase evolved into a novel toxin by losing its ancestral function and acquiring a new role in targeting Aurora kinase A.

The paper investigates how interdependent protein interactions evolve by studying toxin-antidote elements, finding that toxins and antidotes can arise simultaneously through the duplication of a regulatory module.

This study uses ultrastructure expansion microscopy to investigate FPC biogenesis in Trypanosoma brucei, identifying novel structures and tracking key proteins during cell division.