Rejuvenating aged osteoprogenitors for bone repair
Joshua Reeves, Pierre Tournier, Pierre Becquart, Robert Carton, Yin Tang, Alessandra Vigilante, Dong Fang, Shukry James Habib
This study identifies age-related impairments in bone healing and presents a rejuvenation strategy combining Wnt-mediated osteoprogenitor expansion and intermittent fasting to restore youthful bone repair in aged mice.
bioRxiv · Oct 22, 2024Cell Biology