Deficiency of SYCP3-related XLR3 Disrupts the Initiation of Meiotic Sex Chromosome Inactivation in Mouse Spermatogenesis
Natali S. Sobel Naveh, Robert J. Foley, Katelyn R. DeNegre, Tristan C. Evans, Anne Czechanski, Laura G. Reinholdt, Michael J. O’Neill
This study shows that Xlr3 deficiency disrupts DDR factor recruitment to the XY body, leading to MSCI breakdown and spermatogenic defects in mice.
bioRxiv · Mar 30, 2021 · PreprintGenetics