Beta-driven closed-loop deep brain stimulation can compromise human motor behavior in Parkinson’s Disease
Iñaki Iturrate, Stephanie L Martin, Ricardo Chavarriaga, Bastien Orset, Robert Leeb, Aleksander Sobolewski, Étienne Pralong, Mayté Castro Jiménez, David H Benninger, Jocelyne Bloch, José del R. Millán
This study shows that closed-loop DBS in Parkinson’s Disease can alter motor performance during specific movement intervals, particularly by increasing submovements and delaying movement termination.
bioRxiv · Jul 9, 2019 · PreprintNeuroscience