Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients
Sandra García‐Mulero, Roberto Fornelino, Marco Punta, Stefano Lise, Mar Varela, L.P. del Carpio, Rafael Moreno, Marcel Costa-García, Dietmar Rieder, Zlatko Trajanoski, Alena Gros, Ramón Alemany, Josep Maria Piulats, Rebeca Sanz Pamplona
The paper assesses the immunogenic potential of GNAQ and GNA11 mutations in uveal melanoma using genomic and transcriptomic data, finding Q209L mutations are more immunogenic than Q209P.
OncoImmunology · Oct 24, 2023Peer-reviewedGenomics