Josep Maria Piulats

The paper assesses the immunogenic potential of GNAQ and GNA11 mutations in uveal melanoma using genomic and transcriptomic data, finding Q209L mutations are more immunogenic than Q209P.

The paper presents a bioinformatics method to detect Merkel cell polyomavirus insertions in whole exome sequencing data of Merkel cell carcinoma samples, achieving 100% sensitivity and 62.5% specificity.

This study identifies genomic and transcriptomic traits associated with immune-phenotypes in 9,403 solid tumors across 29 cancers, revealing patterns linked to immune evasion and tumor progression.