Rebeca Sanz Pamplona

Integrative multi-omics reveals PARP14 as a key IFNγ-regulated mediator of metastatic progression in Ewing sarcoma.

This study identifies PARP14 as a key IFNγ-regulated mediator of metastatic progression in Ewing sarcoma through multi-omics analyses and functional experiments.

Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

The paper assesses the immunogenic potential of GNAQ and GNA11 mutations in uveal melanoma using genomic and transcriptomic data, finding Q209L mutations are more immunogenic than Q209P.

NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice

NAP-CNB is a web server tool that predicts MHC-I-restricted T cell epitopes in mice using recurrent neural networks, achieving an AUC of 0.95 for H-2 peptide ligands.

Copy-number intratumor heterogeneity contributes to predict relapse in chemotherapy-naive stage II colon cancer

The paper identifies copy-number intratumor heterogeneity as a predictor of relapse in stage II colon cancer, improving risk prediction beyond clinicopathological markers.

Detection of Merkel cell polyomavirus using whole exome sequencing data

The paper presents a bioinformatics method to detect Merkel cell polyomavirus insertions in whole exome sequencing data of Merkel cell carcinoma samples, achieving 100% sensitivity and 62.5% specificity.