GPR27 mediates adrenergic ligands-induced transinhibition of EGFR
Sorina Andreea Anghel, Rodica Aura Badea, Cosmin Trif, Teodora Stratulat, Cristiana Trita, Diana Georgiana Navligu, Stefana Maria Petrescu, Alexandru Babeș, Costin-Ioan Popescu, Cristin Coman, Julien Hanson, Sorin Tunaru
This study shows GPR27 mediates adrenergic ligand-induced transinhibition of EGFR through dephosphorylation of c-Src and EGFR, independent of G-proteins and β-arrestins.
bioRxiv · Mar 12, 2025 · PreprintCell Biology