Author

Stefana Maria Petrescu

Institute of BiochemistryORCID 0000-0002-4047-0811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Cristian V. A. MunteanuiD· 2 shared Gabriela N. ChirițoiuiD· 2 shared Simona GheneaiD· 2 shared Alexandru BabeșiD· 1 shared Andrea LiaiD· 1 shared Andreas BenderiD· 1 shared Andrew QuigleyiD· 1 shared Angelo SantinoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Cristian V. A. MunteanuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel IL-1β reporter assay identifies tolcapone as a caspase-1 suppressor targeting pyroptosis in endotoxemia

Gabriela N. Chirițoiu, Simona Ghenea, Gheorghița Isvoranu, Julien Villeneuve, Cristian V. A. Munteanu, Cristian Pop, Andreas Bender, Stefana Maria Petrescu, Marioara Chiritoiu‐Butnaru

The paper develops a CRISPR-based IL-1β reporter assay to identify tolcapone as a caspase-1 inhibitor that suppresses pyroptosis in endotoxemia.

bioRxiv · Jul 21, 2026 · PreprintImmunology

GPR27 mediates adrenergic ligands-induced transinhibition of EGFR

Sorina Andreea Anghel, Rodica Aura Badea, Cosmin Trif, Teodora Stratulat, Cristiana Trita, Diana Georgiana Navligu, Stefana Maria Petrescu, Alexandru Babeș, Costin-Ioan Popescu, Cristin Coman, Julien Hanson, Sorin Tunaru

This study shows GPR27 mediates adrenergic ligand-induced transinhibition of EGFR through dephosphorylation of c-Src and EGFR, independent of G-proteins and β-arrestins.

bioRxiv · Mar 12, 2025 · PreprintCell Biology

C-terminal domain mobility underpins substrate engagement by the Chaetomium thermophilum EDEM:PDI ERAD-L checkpoint complex

Charlie J. Hitchman, Andrea Lia, Mohammed Bhogadia, Geander M. Pessoa, Gabriela N. Chirițoiu, Cristian V. A. Munteanu, Juan Ortigosa, Jorge Octavio Lannot, Simona Ghenea, Ikuo Wada, Maria De Benedictis, Gábor Tax, Yusupha Bayo, Irene Crescioli, Laura Sanna, , Pietro Roversi

The paper determines Cryo-EM structures of the EDEM:PDI complex with and without a substrate, revealing how disulfide bonds regulate conformational changes essential for substrate engagement.

bioRxiv · Jan 29, 2025 · PreprintBiochemistry