Astrocytic glutamate uptake coordinates experience-dependent, eye-specific refinement in developing visual cortex
Grayson O. Sipe, Jeremy Petravicz, Rajeev Vijay Rikhye, Rodrigo I. Garcia, Nikolaos Mellios, Mriganka Sur
This study shows that astrocytic glutamate uptake via GLT1 is essential for experience-dependent refinement of ipsilateral eye inputs in the visual cortex, with disruptions causing altered binocular matching and plasticity.
Glia · Mar 6, 2021Peer-reviewedNeuroscience