Nikolaos Mellios

This study identifies region-specific neuroimmune gene expression changes in adult mice following prenatal alcohol exposure, revealing proinflammatory pathways and transcriptional regulators linked to FASD.

This paper identifies a brain-enriched circRNA in blood that predicts response to SSRI antidepressants and is regulated by 5-HT2A and BDNF signaling.

This study identifies circHomer1 as a circRNA critical for synaptic development and experience-dependent plasticity in mouse visual cortex through transcriptome analysis and knockdown experiments.

This study identifies transcriptomic changes in cortical neurons exposed to early chronic ethanol, highlighting altered pathways and a caudal molecular shift associated with FASD.

This study shows that astrocytic glutamate uptake via GLT1 is essential for experience-dependent refinement of ipsilateral eye inputs in the visual cortex, with disruptions causing altered binocular matching and plasticity.