Author

Ronald D. Vale

Primary ORCID profile (0000-0003-3460-2758 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Ronald D. ValeiD5 papers · Howard Hughes Medical Institute

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1

Frequent Co-Authors

Courtney M. Schroeder· 1 shared Minhaj Sirajuddin· 1 shared Richard J McKenney· 1 shared Walter Huynh· 1 shared

Activity by Year

2015-2016 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

Courtney M. Schroeder

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2 papers

Recent·Most cited

Assembly and Activation of Dynein-Dynactin by the Cargo Adaptor Protein Hook3

Courtney M. Schroeder, Ronald D. Vale

This study identifies structural features of Hook3 that enable its interaction with dynein and dynactin, revealing how cargo adaptors form processive motor complexes.

bioRxiv · Apr 8, 2016Biochemistry

Tyrosination of α-Tubulin Controls The Initiation of Processive Dynein-Dynactin Motility

Richard J McKenney, Walter Huynh, Ronald D. Vale, Minhaj Sirajuddin

This study shows that tyrosination of α-tubulin enhances dynein-dynactin motility initiation, with detyrosinated tubulin reducing motility by ~4-fold.

bioRxiv · Sep 25, 2015Biophysics