Ronald D. Vale

This study uses HiT-FRAP to show that ribosome assembly state affects nucleolar dynamics and morphology through interactions with NPM1.

This study investigates how the neck linker's conformation affects kinesin-1's stepping mechanism by analyzing its kinetic effects on ATP and microtubule interactions.

The paper identifies a regulatory helix in TRAK that mediates switching between kinesin- and dynein-driven mitochondrial transport in response to stress.

The paper shows that flanking sequences of CAG repeat-containing RNA affect its toxicity, non-ATG translation, and cytoplasmic aggregation, linking these to neurodegenerative disease mechanisms.

The paper introduces a two-color localization method to measure nanometer-scale distances between fluorophores with high accuracy, revealing a 4 nm conformational change in dynein.