The Signaling Pathway of a Bacterial Two-Component System Determined by cryo-EM
Prabin Karki, Carolina Hernández, Joshua H. Mendez, William C. Budell, David Menendez, Shemiran Kanou, Sorayya Razavi, Pakhshan Espoukeh, Rotan Abuhashish, Dorina Bizhga, Shibom Basu, Tek Narsingh Malla, Peter Schwander, Emina A. Stojković, Marius Schmidt
This study uses cryo-EM to determine the structure of a light-regulated bacterial two-component system, revealing how light affects signaling through changes in histidine kinase and response regulator interactions.
bioRxiv · Oct 15, 2026 · PreprintBiophysics