The lupus autoantigen La is an Xist-binding protein involved in Xist folding and cloud formation
Norbert Ha, Nan Ding, Ru Hong, Rubing Liu, Xavier Roca, Yingyuan Luo, Xiaowei Duan, Xiao Wang, Peiling Ni, Haiyang Wu, Li‐Feng Zhang, Lingyi Chen
This study identifies La as an Xist-binding protein essential for X chromosome inactivation, showing its role in Xist folding and cloud formation through functional and imaging analyses.
Nucleic Acids Research · Oct 13, 2021Peer-reviewedMolecular Biology