TOX enforces the immunosuppressive program of tumor-infiltrating regulatory T cells
Seong-Jin Park, Dong Jin Park, Myeong Joon Kim, Geoffrey Kelly, Ruihua Zhang, Gamin Kim, Joon Jeong, Seunghee Kim‐Schulze, Hye Ryun Kim, K I Kim, Sang‐Jun Ha
This study identifies TOX as a critical regulator of tumor-infiltrating regulatory T cells, showing its role in maintaining immunosuppression and its potential as a therapeutic target.
bioRxiv · Jun 24, 2026 · PreprintImmunology