OpenBase: a universal framework for high-accuracy single-molecule detection of diverse non-canonical DNA bases using nanopore sequencing
Zhen-Dong Zhong, Ying-Yuan Xie, Rujia Luo, Hongxuan Chen, Zhi-Shuo Qiao, Zehui Ren, Zhang Zhang, Guan‐Zheng Luo
OpenBase provides a framework for high-accuracy detection of diverse non-canonical DNA bases using nanopore sequencing through standardized training data and deep learning models.
bioRxiv · May 16, 2026 · PreprintBioinformatics