Mutant huntingtin protein alters the response of microglial cells to inflammatory stimuli
David W. Donley, Ryan Nelson, Jason P. Gigley, Jonathan H. Fox
This study shows that mutant huntingtin protein alters microglial responses to different inflammatory stimuli, reducing lipopolysaccharide-induced cytokines but increasing interleukin-6-induced nitric oxide.
bioRxiv · Feb 15, 2019 · PreprintNeuroscience