A New Class of Precision Therapeutics that Inhibit Prostate Cancer Mediated Bone Destruction
Fangfang Qiao, Ryan R. Gordon, Abhinandan Pattanayak, Wenqi Li, Jaclyn Knibbe, Katelyn L. O’Neill, Weining Chen, Prathap Reddy Mukthapuram, Amarnath Natarajan, Raymond C. Bergan
This paper develops BTE-EN1, a compound that inhibits prostate cancer-mediated bone destruction by targeting cell motility and osteoclast activity, showing efficacy in mice.
bioRxiv · May 20, 2025 · PreprintCancer Biology