Human Accelerated Regions regulate gene networks implicated in apical-to-basal neural progenitor fate transitions
Mark Alan Noble, Yu Ji, Kristina Yim, Je Won Yang, Matheo Morales, Reem Abu-Shamma, Atreyo Pal, Ryan R. Poulsen, Marybeth Baumgartner, James P. Noonan
The paper identifies human accelerated regions (HARs) that regulate gene networks involved in neural progenitor fate transitions, specifically affecting apical-to-basal polarity and cortical development.
bioRxiv · Jun 30, 2024 · PreprintNeuroscience