Matheo Morales

This study shows that the human-specific HAR HACNS1 drives opposing heterochronic changes in craniofacial and limb development through altered gene regulatory networks.

The paper maps chromatin interactions of Human Accelerated Regions (HARs) in human and chimpanzee neural stem cells to identify gene targets and their role in neurodevelopment.

The paper identifies human accelerated regions (HARs) that regulate gene networks involved in neural progenitor fate transitions, specifically affecting apical-to-basal polarity and cortical development.