Author

S. A. Gayther

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K. Lawrenson· 3 shared R. I. Corona· 3 shared A. Gusev· 2 shared B. Y. Karlan· 2 shared J. Reddy· 2 shared J.-H. Seo· 2 shared M. L. Freedman· 2 shared X. Lin· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

K. Lawrenson

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMar 22, 2023

Rare germline genetic variation in PAX8 transcription factor binding sites and susceptibility to epithelial ovarian cancer

S. A. M. Ezquina, M. Jones, E. Dicks…·P. D. P. Pharoah

This study investigates rare germline variation in PAX8 binding sites for ovarian cancer risk using burden testing but finds no significant association.

DOI 10.1101/2023.03.22.23287587

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivNov 12, 2019

Predicting master transcription factors from pan-cancer expression data

J. Reddy, M. A. S. Fonseca, R. I. Corona…·K. Lawrenson

This paper introduces CaCTS, an algorithm that identifies candidate master transcription factors (MTFs) across 34 cancer types using RNA-seq data, revealing novel MTFs and functional groupings.

DOI 10.1126/sciadv.abf6123

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivFeb 1, 2019

Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer

R. I. Corona, J.-H. Seo, X. Lin…·K. Lawrenson

The paper identifies histotype-specific regulatory elements in ovarian cancer by integrating chromatin landscapes and somatic mutations, highlighting the PAX8 pathway's role in tumor development.

DOI 10.1038/s41467-020-15951-0

humanChIP-seq

𝕏 PostBluesky