S. A. McGrath-Morrow

Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in ataxia telangiectasia

This study uses bulk RNA-seq to identify inflammatory phenotypes in ataxia telangiectasia by analyzing peripheral blood mononuclear cells.

DNA methyltransferase inhibition induces dynamic gene expression changes in lung CD4+ T cells of neonatal mice with E. coli pneumonia

The paper shows that DNA methyltransferase inhibition in neonatal mice with E. coli pneumonia reduces methylation of interferon-responsive genes, shifting gene expression toward a juvenile-like profile.

Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli

This study compares immune responses in neonatal and juvenile mice to E. coli pneumonia, identifying age-related differences in cellular dynamics and gene expression that may explain increased neonatal susceptibility.