Nanoneedles for targeted siRNA silencing of p16 in the Human Corneal Endothelium
E. Maurizi, D. A. Martella, D. Schiroli, A. Merra, S. A. Mustfa, G. Pellegrini, C. Macaluso, C. Chiappini
This study demonstrates that nanoneedles can deliver p16-targeting siRNA to human corneal endothelial cells, inducing p16 silencing and increasing cell proliferation without toxicity.
bioRxiv · May 27, 2022 · PreprintBioengineering