Author

G. Pellegrini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Merra· 3 shared C. Macaluso· 2 shared D. Schiroli· 2 shared E. Maurizi· 2 shared A. Villa· 1 shared A. Vukolic· 1 shared B. Gouyou· 1 shared C. Chiappini· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

A. Merra

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Towards Clinical-Grade Bioengineered Airways: A Study on Stem Cell Renewal and Epithelial Differentiation

D. Adamo, V. G. Genna, G. Galaverni, C. Chiavelli, A. Merra, F. Lepore, F. Boraldi, D. Quaglino, J. Evangelista, F. Lococo, G. Pellegrini

This study develops a clinical-grade culture system to expand and differentiate primary human airway epithelial cells, identifying stem cell subpopulations and validating their regenerative potential for tissue engineering.

bioRxiv · Dec 28, 2023 · PreprintCell Biology

GSK3 inhibition reverts mesenchymal transition in human primary corneal endothelial cells

E. Maurizi, A. Merra, C. Macaluso, D. Schiroli, G. Pellegrini

This study shows that GSK3 inhibition with CHIR99021 prevents mesenchymal transition in human corneal endothelial cells, preserving their morphology and phenotype.

bioRxiv · Nov 25, 2022 · PreprintCell Biology

Nanoneedles for targeted siRNA silencing of p16 in the Human Corneal Endothelium

E. Maurizi, D. A. Martella, D. Schiroli, A. Merra, S. A. Mustfa, G. Pellegrini, C. Macaluso, C. Chiappini

This study demonstrates that nanoneedles can deliver p16-targeting siRNA to human corneal endothelial cells, inducing p16 silencing and increasing cell proliferation without toxicity.

bioRxiv · May 27, 2022 · PreprintBioengineering

SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1α

P. Simmler, C. Cortijo, L. M. Koch, P. Galliker, M. Schaefer, S. Angori, H. A. Bolck, C. Mueller, A. Vukolic, P. Mirtschink, Y. Christinat, N. R. Davidson, K.-V. Lehmann, G. Pellegrini, C. Pauli, , G. Schwank

This study shows SF3B1 promotes tumor malignancy by co-activating HIF1α through a splicing-independent mechanism, enhancing hypoxia response element binding and target gene expression.

bioRxiv · Nov 10, 2020Cell Biology

The antibody-based delivery of interleukin-12 to solid tumors boosts NK and CD8+ T cell activity and synergizes with immune check-point inhibitors

E. Puca, P. Probst, M. Stringhini, P. Murer, G. Pellegrini, S. Cazzamalli, C. Hutmacher, B. Gouyou, S. Wulhfard, M. Matasci, A. Villa, D. Neri

This paper describes a fusion protein that delivers interleukin-12 to tumors, enhancing NK and CD8+ T cell activity and synergizing with checkpoint inhibitors.

bioRxiv · Jul 3, 2019Cancer Biology