Symmetry reduction in a hyperpolarization-activated homotetrameric ion channel
M. S. Dickinson, M. Gupta, S. A. Pourmal, M. Bi, R. M. Stroud
The paper determines the structure of the hyperpolarization-activated channel AKT1 from Arabidopsis thaliana and shows it undergoes symmetry reduction to regulate electrical activation.
bioRxiv · Sep 20, 2021Biophysics