Author

R. M. Stroud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:Arabidopsis· 2 Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. S. Dickinson· 3 shared A. Frost· 1 shared A. Sali· 1 shared B. Bräuning· 1 shared B. Schulman· 1 shared C. Navarro-Retamal· 1 shared C. S. Craik· 1 shared D. Becker· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

M. S. Dickinson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure and dynamics of the essential endogenous mycobacterial polyketide synthasePks13

S. K. Kim, M. S. Dickinson, J. S. Finer-Moore, Z. Guan, R. M. Kaake, I. Echeverria, J. Chen, E. H. Pulido, A. Sali, N. J. Krogan, O. S. Rosenberg, R. M. Stroud

This paper determines the structure and dynamics of the mycobacterial polyketide synthase Pks13 using cryoEM and complementary techniques, revealing intermediate states and substrate binding.

bioRxiv · Jan 27, 2023Biochemistry

Vicia faba TPC1, a genetically encoded variant of the vacuole Two Pore Channel 1, is hyperexcitable

J. Lu, I. Dreyer, M. S. Dickinson, S. Panzer, D. Jaslan, C. Navarro-Retamal, D. Geiger, U. Terpitz, D. Becker, R. M. Stroud, I. Marten, R. Hedrich

This paper identifies a hyperexcitable variant of the TPC1 channel in Vicia faba, showing it differs from Arabidopsis in Ca2+ sensitivity and vacuole excitability.

bioRxiv · Dec 22, 2021Plant Biology

Symmetry reduction in a hyperpolarization-activated homotetrameric ion channel

M. S. Dickinson, M. Gupta, S. A. Pourmal, M. Bi, R. M. Stroud

The paper determines the structure of the hyperpolarization-activated channel AKT1 from Arabidopsis thaliana and shows it undergoes symmetry reduction to regulate electrical activation.

bioRxiv · Sep 20, 2021Biophysics

Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody

J. Eriksen, F. Li, R. M. Stroud, R. H. Edwards

This study develops isoform-specific antibodies against VGLUT2 to investigate allosteric inhibition mechanisms and their physiological roles.

bioRxiv · Jun 16, 2021Biochemistry

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

L. E. Miller-Vedam, B. Bräuning, K. D. Popova, N. T. Schirle Oakdale, J. L. Bonnar, J. R. Prabu, E. A. Boydston, N. Sevillano, M. J. Shurtleff, R. M. Stroud, C. S. Craik, B. Schulman, A. Frost, J. S. Weissman

The paper reveals the structural and mechanistic basis of EMC's role in biogenesis of distinct transmembrane proteins through cryo-EM structures and functional studies.

bioRxiv · Sep 2, 2020Biophysics