Author

S. Barbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:bacteria (other)· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

T. Schiex· 2 shared A. K. Padhi· 1 shared D. Dessaux· 1 shared D. Simoncini· 1 shared F. Boudsocq· 1 shared G. Cioci· 1 shared J. Vucinic· 1 shared J.-Y. Bouet· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

T. Schiex

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Designing symmetrical multi-component proteins using a hybrid generative AI approach

D. Dessaux, S. Buchet, L. Barthe, M. Defresne, G. Cioci, S. de Givry, L. F. Garcia-Alles, T. Schiex, S. Barbe

This paper introduces a hybrid generative AI approach to design multi-component proteins by combining deep learning and automated reasoning, showing improved performance over existing methods in creating heteromeric assemblies.

bioRxiv · Jun 13, 2024 · PreprintBioengineering

Three ParA dimers cooperatively assemble on type Ia partition promoters

F. Boudsocq, M. Salhi, S. Barbe, J.-Y. Bouet

The paper shows three ParAF dimers cooperatively bind to overlapping DNA motifs in the promoter region of type Ia plasmid partition systems.

bioRxiv · May 10, 2021Biochemistry

Seven amino acid types suffice to reconstruct the core fold of RNA polymerase

S. Yagi, A. K. Padhi, J. Vucinic, S. Barbe, T. Schiex, R. Nakagawa, D. Simoncini, K. Y. J. Zhang, S. Tagami

The paper reconstructs the DPBB fold using only seven amino acid types, suggesting it could have emerged with the early genetic code.

bioRxiv · Feb 22, 2021Biochemistry