Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors
A. Ruiz, S. Benucci, U. Duthaler, C. P. Bachmann, M. Franchini, F. Noreen, L. Pietrangelo, F. Protasi, S. Treves, F. Zorzato
This study treats a mouse model of congenital myopathy with HDAC and DNA methyltransferase inhibitors, improving muscle strength and RyR1 protein content.
bioRxiv · Nov 9, 2021Physiology