Animal Behavior & CognitionbioRxiv
The immunomodulatory effect of IrSPI, a tick salivary gland serine protease inhibitor involved in Ixodes ricinus tick feeding
A. A. Blisnick, L. Simo, C. Grillon…·S. I. Bonnet
This paper identifies IrSPI, a tick salivary serine protease inhibitor, and shows it modulates the host immune response by inhibiting CD4+ T cell proliferation and altering cytokine secretion.
DOI 10.3390/vaccines7040148