Transcutaneous penetration of a single-chain variable fragment (scFv) compared to a full-size antibody: potential tool for Atopic Dermatitis (AD) treatment
A. Baylet, R. Vyumvuhore, M. Laclaverie, L. Marchand, C. Mainzer, S. Bordes, B. Closs-Gonthier, L. Delpy
This study compares the transcutaneous penetration of a single-chain variable fragment (scFv) and a full-size antibody, showing scFv penetrates deeper and more effectively neutralizes hIL-4 in AD models.
bioRxiv · Jan 29, 2021Immunology