HIV, asymptomatic STI, and the rectal mucosal immune environment among young men who have sex with men
V. E. Van Doren, S. A. Smith, Y.-J. Hu, G. Tharp, S. Bosinger, C. G. Ackerley, P. M. Murray, R. R. Amara, P. K. Amancha, R. A. Arthur, H. R. Johnston, C. F. Kelley
This study examines the immunologic effects of HIV and asymptomatic bacterial STIs on the rectal mucosa in YMSM, finding HIV alters cellular composition while STIs increase pathogenic bacteria and inflammation in HIV-positive individuals.
bioRxiv · Feb 20, 2023Immunology