Author

H. R. Johnston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. I. Marcus· 2 shared C.-S. Seong· 2 shared H. Claussen· 2 shared H. Fu· 2 shared J. Koo· 2 shared M. Gilbert-Ross· 2 shared R. A. Arthur· 2 shared S. S. Ramalingam· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

A. I. Marcus

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer

J. Koo, C.-S. Seong, R. E. Parker, B. Dwivedi, R. A. Arthur, A. R. Dinasarapu, H. R. Johnston, H. Claussen, C. Tucker-Burden, S. S. Ramalingam, H. Fu, W. Zhou, A. I. Marcus, M. Gilbert-Ross

This study identifies the ALK2/BMP6 iron homeostasis pathway as a therapeutic target in LKB1-mutant lung cancer using live-cell imaging and transcriptome analysis.

bioRxiv · Jun 14, 2023 · PreprintCancer Biology

HIV, asymptomatic STI, and the rectal mucosal immune environment among young men who have sex with men

V. E. Van Doren, S. A. Smith, Y.-J. Hu, G. Tharp, S. Bosinger, C. G. Ackerley, P. M. Murray, R. R. Amara, P. K. Amancha, R. A. Arthur, H. R. Johnston, C. F. Kelley

This study examines the immunologic effects of HIV and asymptomatic bacterial STIs on the rectal mucosa in YMSM, finding HIV alters cellular composition while STIs increase pathogenic bacteria and inflammation in HIV-positive individuals.

PLOS Pathogens · May 30, 2023Peer-reviewedImmunology

Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis.

C.-S. Seong, C. Huang, A. C. Boese, Y. Hou, J. Koo, J. K. Mouw, M. Rupji, G. Joseph, H. R. Johnston, H. Claussen, J. M. Switchenko, M. Behera, M. Churchman, J. M. Kolesar, S. M. Arnold, , M. Gilbert-Ross

The paper shows that loss of HD-PTP, a tumor suppressor, promotes RAS-driven oncogenesis and is associated with adenosquamous lung cancer, suggesting it as a therapeutic target.

bioRxiv · Jan 26, 2023 · PreprintCancer Biology