New cinnamid and rosmarinic acid-derived compounds biosynthesized in Escherichia coli as Leishmania amazonensis arginase inhibitors
J. A. A. d. S. S. Come, Y. Zhuang, T. Li, S. Brogi, S. Gemma, T. Liu, E. R. da Silva
The paper describes the biosynthesis of new cinnamid and rosmarinic acid-derived compounds in E. coli that inhibit Leishmania amazonensis arginase, with some compounds showing micromolar inhibition.
bioRxiv · Oct 30, 2020 · PreprintBiochemistry