Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients
J. M. Holzinger, M. Toelge, M. Werner, K. U. Ederer, H. I. Siegmund, D. Peterhoff, S. Blaas, N. Gisch, C. Brochhausen-Delius, A. Gessner, S. Bülow
The paper shows that scorpionfish-derived BPI (scoBPI) is effective against drug-resistant Pseudomonas aeruginosa in CF patients, even when human BPI is neutralized by autoantibodies.
bioRxiv · Feb 19, 2023Microbiology