N. Gisch

MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in Drosophila gut during inflammation

This study shows that MprF in Lactiplantibacillus plantarum helps it survive in Drosophila gut during inflammation by reducing immune response and maintaining microbial stability.

Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients

The paper shows that scorpionfish-derived BPI (scoBPI) is effective against drug-resistant Pseudomonas aeruginosa in CF patients, even when human BPI is neutralized by autoantibodies.

Competence remodels the pneumococcal cell wall providing resistance to fratricide and surface exposing key virulence factors

This study shows that competence in Streptococcus pneumoniae is crucial for virulence by increasing surface exposure of virulence factors and providing resistance to fratricide.

A single residue within the MCR-1 protein confers anticipatory resilience

This study identifies a single residue in MCR-1 that modulates its interaction with the ESR system, affecting colistin resistance and bacterial resilience to environmental stressors.

Lupus disease flares are concordant with immune responses to blooms of lipoglycan-expressing Ruminococcus blautia gnavus strains arising from unstable gut microbiota communities

Commensal Streptococcus mitis produces two different lipoteichoic acids of type I and type IV

This paper identifies two distinct lipoteichoic acid (LTA) types in Streptococcus mitis, type IV similar to S. pneumoniae and type I with a unique structure, revealing dual biosynthesis pathways.

Tuberculostearic acid (TSA)-containing phosphatidylinositols as reliable marker to determine Mycobacterium tuberculosis bacterial burden

This study identifies TSA-containing phosphatidylinositols as reliable markers for quantifying Mycobacterium tuberculosis burden in experimental models and suggests their potential clinical application.