HIV integrase compacts viral DNA into biphasic condensates
P. J. Kolbeck, M. de Jager, M. Gallano, T. Brouns, B. Bekaert, W. Frederickx, S. F. Konrad, S. Van Belle, F. Christ, S. De Feyter, Z. Debyser, L. C. Filion, J. Lipfert, W. Vanderlinden
This study shows HIV integrase compacts viral DNA into biphasic condensates, with the core susceptible to inhibitors and the outer layer resistant.
bioRxiv · Mar 15, 2024 · PreprintBiophysics