Author

T. Brouns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3

Frequent Co-Authors

J. Lipfert· 3 shared W. Vanderlinden· 3 shared P. J. Kolbeck· 2 shared S. De Feyter· 2 shared S. F. Konrad· 2 shared W. Frederickx· 2 shared B. Bekaert· 1 shared B. Menze· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBiophysics

J. Lipfert

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3 papers

Recent·Most cited

HIV integrase compacts viral DNA into biphasic condensates

P. J. Kolbeck, M. de Jager, M. Gallano, T. Brouns, B. Bekaert, W. Frederickx, S. F. Konrad, S. Van Belle, F. Christ, S. De Feyter, Z. Debyser, L. C. Filion, J. Lipfert, W. Vanderlinden

This study shows HIV integrase compacts viral DNA into biphasic condensates, with the core susceptible to inhibitors and the outer layer resistant.

bioRxiv · Mar 15, 2024 · PreprintBiophysics

High-yield, ligation-free assembly of DNA constructs with nucleosome positioning sequence repeats for single molecule manipulation assays

Y.-Y. Lin, T. Brouns, P. J. Kolbeck, W. Vanderlinden, J. Lipfert

This paper describes a method for high-yield DNA construct assembly with nucleosome positioning sequences for single-molecule manipulation assays, demonstrating stable tethers and proof-of-concept measurements on nucleosome dynamics.

bioRxiv · Jan 5, 2023Biophysics

High-throughput AFM analysis reveals unwrapping pathways of H3 and CENP-A nucleosomes

S. F. Konrad, W. Vanderlinden, W. Frederickx, T. Brouns, B. Menze, S. De Feyter, J. Lipfert

The paper uses high-throughput atomic force microscopy to analyze nucleosome unwrapping pathways, revealing differences between H3 and CENP-A nucleosomes.

bioRxiv · Apr 9, 2020Biophysics