Author

Z. Debyser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Christ· 2 shared S. Van Belle· 2 shared A. Bath· 1 shared A. Bruggemans· 1 shared A. Maciejczuk· 1 shared A.-S. Desmet· 1 shared B. Bekaert· 1 shared B. Sodeik· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

F. Christ

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIV integrase compacts viral DNA into biphasic condensates

P. J. Kolbeck, M. de Jager, M. Gallano, T. Brouns, B. Bekaert, W. Frederickx, S. F. Konrad, S. Van Belle, F. Christ, S. De Feyter, Z. Debyser, L. C. Filion, J. Lipfert, W. Vanderlinden

This study shows HIV integrase compacts viral DNA into biphasic condensates, with the core susceptible to inhibitors and the outer layer resistant.

bioRxiv · Mar 15, 2024 · PreprintBiophysics

MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

G. D. Moschonas, L. Delhaye, R. Cooreman, F. Husers, A. Bath, D. De Sutter, E. Parthoens, A.-S. Desmet, A. Maciejczuk, H. Grzesik, S. Lippens, Z. Debyser, B. Sodeik, S. Eyckerman, X. Saelens

This study shows MX2 forms cytoplasmic condensates that mimic nuclear pore complexes to restrict HIV-1 and HSV-1 by trapping viral capsids and preventing nuclear entry.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles

Q. Coucke, N. Parveen, G. S. Fernandez, C. Qian, J. Hofkens, Z. Debyser, J. Hendrix

The paper introduces particle-based phasor-FLIM-FRET to quantify protein-protein interactions in single viral particles, showing it can accurately measure FRET efficiency with low signal intensities.

bioRxiv · May 31, 2023Biophysics

BET-independent MLV integration is retargeted in vivo and selects distinct genomic elements for lymphomagenesis

I. Nombela, M. Michiels, D. Van Looveren, L. Marcelis, S. el Ashkar, S. Van Belle, A. Bruggemans, T. Tousseyn, J. Schwaller, F. Christ, R. Gijsbers, J. De Rijck, Z. Debyser

This study compares BET-dependent and -independent MLV integration in mice, finding that BET proteins influence integration site selection but not tumorigenesis.

bioRxiv · Feb 23, 2022 · PreprintMicrobiology