Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
W. Oosterheert, K. T. Xenaki, V. Neviani, W. Pos, S. Doulkeridou, J. Manshande, N. M. Pearce, L. M. J. Kroon-Batenburg, M. Lutz, P. M. P. van Bergen en Henegouwen, P. Gros
The paper presents crystal and cryo-EM structures of CD9 with nanobodies and EWI-F, revealing a tetrameric arrangement that provides a model for tetraspanin-enriched microdomain assembly.
Life Science Alliance · Nov 1, 2020Peer-reviewedBiophysics