Predicting antiviral resistance mutations in SARS-CoV-2 main protease with computational and experimental screening
V. M. Sasi, S. Ullrich, J. Ton, S. E. Fry, J. Johansen-Leete, R. J. Payne, C. Nitsche, C. J. Jackson
This study identifies resistance mutations in SARS-CoV-2 main protease to the drug Nirmatrelvir using computational screening and experimental validation.
Biochemistry · Nov 3, 2022Peer-reviewedBiochemistry