Author

J. Ton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:Arabidopsis· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. J. Jackson· 2 shared A. M. Damry· 1 shared B. M. Lee· 1 shared C. Nitsche· 1 shared C. Yu· 1 shared C.-N. Tao· 1 shared D. Matthews· 1 shared F. Johannes· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

C. J. Jackson

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Author profile →

5 papers

Recent·Most cited

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

V. Vongsouthi, R. Georgelin, D. Matthews, J. Saunders, B. M. Lee, J. Ton, A. M. Damry, R. Frkic, M. A. Spence, C. J. Jackson

This study uses ancestral sequence reconstruction to explore PET-degrading cutinase sequence space, revealing diverse evolutionary pathways and the effectiveness of LASE in mapping fitness landscapes.

bioRxiv · Apr 25, 2024Biochemistry

NPR1 protects young leaves from systemic salicylic acid-induced damage during bacterial infection

H. Horak, S. A. Rolfe, J. Ton, J. E. Gray

The paper shows NPR1 suppresses systemic SA-induced damage in young leaves during bacterial infection, protecting them from autoimmune harm.

bioRxiv · Aug 21, 2023 · PreprintPlant Biology

An evolutionary epigenetic clock in plants

N. Yao, Z. Zhang, L. Yu, R. Hazarika, C. Yu, H. Jang, L. M. Smith, J. Ton, L. Liu, J. Stachowicz, T. B. H. Reusch, R. J. Schmitz, F. Johannes

This paper introduces an epigenetic clock based on stochastic DNA methylation changes in plants, enabling high-resolution temporal analysis of phylogenetic relationships.

bioRxiv · Mar 15, 2023Evolutionary Biology

Predicting antiviral resistance mutations in SARS-CoV-2 main protease with computational and experimental screening

V. M. Sasi, S. Ullrich, J. Ton, S. E. Fry, J. Johansen-Leete, R. J. Payne, C. Nitsche, C. J. Jackson

This study identifies resistance mutations in SARS-CoV-2 main protease to the drug Nirmatrelvir using computational screening and experimental validation.

Biochemistry · Nov 3, 2022Peer-reviewedBiochemistry

A single amino acid transporter controls the uptake of priming-inducing beta-amino acids and the associated trade-off between induced resistance and plant growth.

C.-N. Tao, W. Buswell, P. Zhang, H. Walker, I. Johnson, R. Schwarzenbacher, J. Ton

The paper identifies IRI1/LHT1 as the main transporter for beta-amino acids, showing its role in plant resistance and growth trade-offs.

bioRxiv · Mar 17, 2022Plant Biology