Author

S. Eccles

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. De Haven Brandon· 1 shared A. Hayes· 1 shared B. Al-Lazikani· 1 shared C. Zhang· 1 shared F. Raynaud· 1 shared J. Freeman· 1 shared M. Elbanna· 1 shared P. A. Clarke· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. De Haven Brandon

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1 paper

Recent·Most cited

Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases

C. Zhang, S. R. Stockwell, M. Elbanna, R. Ketteler, J. Freeman, B. Al-Lazikani, S. Eccles, A. De Haven Brandon, F. Raynaud, A. Hayes, P. A. Clarke, P. Workman, S. Mittnacht

This study shows that MET/FAK signaling can activate CDK2 independently of CDK4/6, leading to cell division, and suggests targeting MET/FAK could enhance CDK4/6 inhibitor therapies.

bioRxiv · Apr 8, 2019Cancer Biology