Parasite-Induced IFN-g Regulates Host Defense via CD115 and mTOR-Dependent Mechanism of Tissue-Resident Macrophage Death
A. Martin, S. Giri, A. Safronova, S. Eliseeva, S. Kwok, F. Yarovinsky
This study shows that IFN-gamma induces CD115 and mTOR-dependent death of tissue-resident macrophages, enhancing host resistance to Toxoplasma gondii.
bioRxiv · Jun 23, 2023Immunology