HuR-miRNA complex Activates RAS GTPase RalA to Facilitate Endosome Targeting and Extracellular Export of miRNAs
S. Ghosh, S. H. Choudhury, K. Mukherjee, S. N. Bhattacharyya
The paper develops an in vitro assay to study miRNA packaging into endosomes and shows that HuR-miRNA complexes activate RalA GTPase to facilitate miRNA import and export.
bioRxiv · Jun 22, 2023Biochemistry