Integrin signaling is critical for myeloid-mediated support of T-cell acute lymphoblastic leukemia
A. Lyu, S. H. Nam, R. S. Humphrey, T. A. Durham, Z. Hu, D. Arasappan, T. M. Horton, L. I. R. Ehrlich
This study identifies integrin-mediated adhesion and FAK/PYK2 signaling as critical for myeloid cell support of T-ALL, showing their role in survival and progression.
bioRxiv · Jan 5, 2022Cancer Biology